/* Layout: a sticky study header with view tabs; one reading column for the report, a wider working column for charts and the citing-paper table.
   Colour follows pubmed-stream's own chart code: blue for the paper's finding, orange for doubts, aqua for general citations, grey for unread. */
:root {
  --bg: #f9f9f7; --surface: #fcfcfb; --ink: #0b0b0b; --ink-2: #52514e; --muted: #898781;
  --grid: #e1e0d9; --edge: #c3c2b7; --border: rgba(11,11,11,.10); --wash: rgba(11,11,11,.04);
  --accent: #2a78d6; --accent-ink: #1c5cab;
  --series-1: #2a78d6; --series-2: #eb6834; --series-3: #1baf7a; --other: #a3a29c;
  --font-ui: "IBM Plex Sans", system-ui, -apple-system, "Segoe UI", sans-serif;
  --font-doc: "IBM Plex Serif", Georgia, "Times New Roman", serif;
  --font-mono: "IBM Plex Mono", ui-monospace, SFMono-Regular, Menlo, monospace;
}
@media (prefers-color-scheme: dark) {
  :root:not([data-theme="light"]) {
    --bg: #0d0d0d; --surface: #1a1a19; --ink: #f0efec; --ink-2: #c3c2b7; --muted: #898781;
    --grid: #2c2c2a; --edge: #383835; --border: rgba(255,255,255,.10); --wash: rgba(255,255,255,.05);
    --accent: #3987e5; --accent-ink: #86b6ef;
    --series-1: #3987e5; --series-2: #d95926; --series-3: #199e70; --other: #6b6a66;
    color-scheme: dark;
  }
}
:root[data-theme="dark"] {
  --bg: #0d0d0d; --surface: #1a1a19; --ink: #f0efec; --ink-2: #c3c2b7; --muted: #898781;
  --grid: #2c2c2a; --edge: #383835; --border: rgba(255,255,255,.10); --wash: rgba(255,255,255,.05);
  --accent: #3987e5; --accent-ink: #86b6ef;
  --series-1: #3987e5; --series-2: #d95926; --series-3: #199e70; --other: #6b6a66;
  color-scheme: dark;
}
* { box-sizing: border-box; }
body { margin: 0; background: var(--bg); color: var(--ink); font-family: var(--font-ui); font-size: 15px; line-height: 1.5; }
body::before { content: ""; position: fixed; inset: 0 0 auto; height: env(safe-area-inset-top, 0px); z-index: 10; background: var(--surface); }
a { color: var(--accent-ink); }
a:focus-visible, button:focus-visible, [tabindex="0"]:focus-visible, select:focus-visible, input:focus-visible { outline: 2px solid var(--accent); outline-offset: 2px; }
h1, h2, h3, h4 { text-wrap: balance; line-height: 1.2; margin: 0; }
h2 { font-size: 1.35rem; font-weight: 600; }
h3 { font-size: 1.05rem; font-weight: 600; }
p { margin: 0; }
.eyebrow { font-size: .72rem; letter-spacing: .08em; text-transform: uppercase; color: var(--muted); font-weight: 500; }
.num { font-variant-numeric: tabular-nums; }

/* header and tabs */
header.top { position: sticky; top: env(safe-area-inset-top, 0px); z-index: 5; background: var(--surface); border-bottom: 1px solid var(--border);
  padding-left: max(16px, env(safe-area-inset-left, 0px)); padding-right: max(16px, env(safe-area-inset-right, 0px)); padding-block: 10px 0; }
.top-inner { max-width: 1120px; margin: 0 auto; display: flex; flex-wrap: wrap; align-items: baseline; gap: 4px 20px; }
.top h1 { font-size: 1.1rem; font-weight: 600; }
.top .sub { color: var(--ink-2); font-size: .85rem; }
.top-bar { max-width: 1120px; margin: 0 auto 4px; display: flex; flex-wrap: wrap; justify-content: space-between; gap: 2px 16px; font-size: .8rem; color: var(--ink-2); }
.top-bar a { color: var(--ink-2); text-decoration: none; }
.top-bar a:hover { color: var(--accent-ink); text-decoration: underline; }
.crumbs .sep { margin: 0 6px; color: var(--muted); }
.top-links { display: flex; gap: 14px; }
nav.tabs { max-width: 1120px; margin: 6px auto 0; display: flex; gap: 2px; overflow-x: auto; scrollbar-width: none; }
nav.tabs::-webkit-scrollbar { display: none; }
nav.tabs a { flex: 0 0 auto; padding: 8px 12px; text-decoration: none; color: var(--ink-2); border-bottom: 2px solid transparent; font-size: .9rem; white-space: nowrap; }
nav.tabs a:hover { color: var(--ink); background: var(--wash); }
nav.tabs a[aria-current="page"] { color: var(--ink); border-bottom-color: var(--accent); font-weight: 500; }

main { padding-left: max(16px, env(safe-area-inset-left, 0px)); padding-right: max(16px, env(safe-area-inset-right, 0px)); padding-block: 24px 64px; }
section.view { max-width: 1120px; margin: 0 auto; display: grid; gap: 28px; }
section.view[hidden] { display: none; }
.lede { font-family: var(--font-doc); font-size: 1.1rem; max-width: 68ch; color: var(--ink); }
.note { color: var(--ink-2); font-size: .9rem; max-width: 72ch; }
.block { display: grid; gap: 12px; }

/* stat tiles */
.tiles { display: grid; grid-template-columns: repeat(auto-fit, minmax(170px, 1fr)); gap: 10px; }
.tile { background: var(--surface); border: 1px solid var(--border); border-radius: 6px; padding: 12px 14px; display: grid; gap: 2px; min-width: 0; }
.tile .v { font-size: 1.7rem; font-weight: 600; line-height: 1.1; }
.tile .l { font-size: .85rem; color: var(--ink); }
.tile .s { font-size: .78rem; color: var(--muted); }
.hero { display: grid; gap: 4px; }
.hero .v { font-size: 3.2rem; font-weight: 600; line-height: 1; }
.hero .l { font-size: 1rem; color: var(--ink-2); max-width: 60ch; }

/* verdict cards */
.three { display: grid; grid-template-columns: repeat(auto-fit, minmax(260px, 1fr)); gap: 12px; }
.card { background: var(--surface); border: 1px solid var(--border); border-radius: 6px; padding: 14px 16px; display: grid; gap: 8px; align-content: start; min-width: 0; }
.card p { font-size: .92rem; color: var(--ink); }
.stripe { border-top: 3px solid var(--series-2); }
.stripe.ok { border-top-color: var(--series-3); }
.stripe.warn { border-top-color: var(--series-1); }

/* timeline */
.timeline { display: grid; gap: 0; border-left: 1px solid var(--edge); margin-left: 6px; }
.timeline > div { display: grid; grid-template-columns: 110px 1fr; gap: 12px; padding: 6px 0 6px 16px; position: relative; font-size: .92rem; }
.timeline > div::before { content: ""; position: absolute; left: -5px; top: 13px; width: 9px; height: 9px; border-radius: 50%; background: var(--edge); }
.timeline > div.key::before { background: var(--series-2); }
.timeline > div.key { font-weight: 500; }
.timeline .d { color: var(--muted); font-variant-numeric: tabular-nums; white-space: nowrap; }
@media (max-width: 480px) { .timeline > div { grid-template-columns: 1fr; gap: 2px; } }

/* figures */
figure { margin: 0; background: var(--surface); border: 1px solid var(--border); border-radius: 6px; padding: 14px 16px 10px; position: relative; display: grid; gap: 6px; min-width: 0; }
figure figcaption { display: grid; gap: 2px; }
figure figcaption .t { font-weight: 600; }
figure figcaption .h { font-size: .85rem; color: var(--ink-2); }
.plot { width: 100%; min-width: 0; }
.plot svg { display: block; width: 100%; height: auto; overflow: visible; }
.legend { display: flex; flex-wrap: wrap; gap: 6px 16px; font-size: .82rem; color: var(--ink-2); }
.legend span { display: inline-flex; align-items: center; gap: 6px; }
.sw { width: 12px; height: 12px; border-radius: 3px; display: inline-block; }
.tip { position: absolute; pointer-events: none; background: var(--ink); color: var(--bg); padding: 6px 9px; border-radius: 4px; font-size: .8rem; line-height: 1.35; display: none; z-index: 3; max-width: 240px; }
.tip b { font-size: .95rem; }
.tip .row { display: flex; gap: 8px; align-items: center; }
.tip .k { width: 10px; height: 3px; border-radius: 2px; display: inline-block; }
details.tableview { font-size: .85rem; }
details.tableview summary { cursor: pointer; color: var(--accent-ink); width: max-content; }
.tableview table { margin-top: 8px; }
svg text { font-family: var(--font-ui); fill: var(--ink-2); font-size: 11px; }
svg .ink { fill: var(--ink); font-weight: 500; }
svg .grid line { stroke: var(--grid); stroke-width: 1; }
svg .base { stroke: var(--edge); stroke-width: 1; }
svg .ev line { stroke: var(--muted); stroke-width: 1; }
svg .ev text { fill: var(--muted); font-size: 10.5px; }
svg .hit { fill: transparent; }
svg .bar.hover { filter: brightness(1.12); }
.charts2 { display: grid; grid-template-columns: repeat(auto-fit, minmax(320px, 1fr)); gap: 12px; }

/* tables */
table { border-collapse: collapse; width: 100%; font-size: .86rem; }
th, td { text-align: left; padding: 6px 8px; border-bottom: 1px solid var(--grid); vertical-align: top; }
th { font-weight: 500; color: var(--ink-2); font-size: .78rem; letter-spacing: .03em; text-transform: uppercase; white-space: nowrap; }
td.num, th.num { text-align: right; font-variant-numeric: tabular-nums; }
.tablewrap { overflow-x: auto; }

/* chips */
.chip { display: inline-flex; align-items: center; gap: 6px; font-size: .78rem; padding: 2px 8px; border: 1px solid var(--border); border-radius: 999px; color: var(--ink); white-space: nowrap; background: var(--surface); }
.chip .dot { width: 8px; height: 8px; border-radius: 50%; display: inline-block; }
.dot.names { background: var(--series-1); } .dot.doubts { background: var(--series-2); } .dot.general { background: var(--series-3); } .dot.unread { background: var(--other); }
.flag { font-size: .72rem; color: var(--ink-2); border: 1px solid var(--border); border-radius: 3px; padding: 0 5px; margin-left: 4px; }

/* citing-paper browser */
.filters { display: flex; flex-wrap: wrap; gap: 8px 12px; align-items: end; }
.filters label { display: grid; gap: 3px; font-size: .78rem; color: var(--ink-2); }
.filters select, .filters input { font: inherit; font-size: .9rem; padding: 5px 8px; border: 1px solid var(--edge); border-radius: 4px; background: var(--surface); color: var(--ink); min-width: 0; }
.filters input[type="search"] { width: 220px; max-width: 100%; }
.quick { display: flex; flex-wrap: wrap; gap: 6px; }
.quick button, .btn { font: inherit; font-size: .82rem; padding: 4px 10px; border: 1px solid var(--edge); background: var(--surface); color: var(--ink); border-radius: 999px; cursor: pointer; }
.quick button:hover, .btn:hover { background: var(--wash); }
.quick button[aria-pressed="true"] { border-color: var(--accent); color: var(--accent-ink); }
.count { font-size: .88rem; color: var(--ink-2); }
.papers { display: grid; gap: 10px; }
.paper { background: var(--surface); border: 1px solid var(--border); border-radius: 6px; padding: 10px 14px; display: grid; gap: 4px; min-width: 0; }
.paper .meta { display: flex; flex-wrap: wrap; gap: 4px 10px; align-items: center; font-size: .82rem; color: var(--ink-2); }
.paper .title { font-weight: 500; }
.paper .title a { color: var(--ink); text-decoration: none; }
.paper .title a:hover { text-decoration: underline; }
.paper .sent { font-family: var(--font-doc); font-size: .95rem; color: var(--ink); }
.paper .sent .cite { display: inline-block; font-family: var(--font-ui); font-size: .72rem; background: var(--series-1); color: #fff; border-radius: 3px; padding: 0 5px; margin: 0 2px; vertical-align: 1px; }
.paper .none { color: var(--muted); font-size: .85rem; }
.more { justify-self: start; }

/* document rendering */
.doc { font-family: var(--font-doc); font-size: 1.05rem; line-height: 1.6; max-width: 72ch; }
.doc h1 { font-size: 1.9rem; font-weight: 600; margin: 0 0 .6em; }
.doc h2 { font-size: 1.4rem; margin: 1.6em 0 .5em; }
.doc h3 { font-size: 1.12rem; margin: 1.3em 0 .4em; }
.doc p { margin: 0 0 .9em; }
.doc ul, .doc ol { padding-left: 1.3em; margin: 0 0 .9em; }
.doc li { margin: .25em 0; }
.doc em { font-style: italic; }
.doc code { font-family: var(--font-mono); font-size: .82em; background: var(--wash); padding: 1px 4px; border-radius: 3px; }
.doc pre { overflow-x: auto; background: var(--wash); padding: 10px 12px; border-radius: 4px; font-size: .82em; }
.doc table { font-family: var(--font-ui); font-size: .85rem; margin: .4em 0 1.2em; display: block; overflow-x: auto; }
.doc th, .doc td { white-space: normal; }
.doc th { text-transform: none; letter-spacing: 0; }
.doc blockquote { margin: 0 0 .9em; padding-left: 1em; border-left: 3px solid var(--edge); color: var(--ink-2); }
.doc hr { border: 0; border-top: 1px solid var(--grid); margin: 1.5em 0; }
.docgrid { display: grid; grid-template-columns: minmax(0, 1fr); gap: 24px; }
@media (min-width: 980px) { .docgrid { grid-template-columns: 220px minmax(0, 1fr); } .toc { position: sticky; top: 96px; align-self: start; } }
.toc { font-size: .85rem; display: grid; gap: 4px; }
.toc a { text-decoration: none; color: var(--ink-2); }
.toc a.h3 { padding-left: 12px; font-size: .8rem; }
.toc a:hover { color: var(--ink); }
.raw { white-space: pre-wrap; font-family: var(--font-mono); font-size: .85rem; }

/* probes */
.qgroup { display: grid; gap: 12px; }
.q { background: var(--surface); border: 1px solid var(--border); border-radius: 6px; padding: 12px 16px; display: grid; gap: 8px; min-width: 0; }
.q .prompt { font-family: var(--font-doc); font-size: 1.02rem; }
.q .exp { font-size: .86rem; color: var(--ink-2); }
.q .exp ul { margin: 2px 0 0; padding-left: 1.2em; }
.q .keys { display: flex; flex-wrap: wrap; gap: 4px; }
.q .keys code { font-family: var(--font-mono); font-size: .75rem; background: var(--wash); padding: 1px 6px; border-radius: 3px; }
.ans { border-top: 1px solid var(--grid); padding-top: 8px; display: grid; gap: 6px; }
.ans .meta { font-size: .8rem; color: var(--ink-2); display: flex; flex-wrap: wrap; gap: 4px 12px; }
.ans .body { font-size: .92rem; }
.ans .body table { display: block; overflow-x: auto; }
.ans details { font-size: .85rem; }
.ans details summary { cursor: pointer; color: var(--accent-ink); }
.ans pre.think { white-space: pre-wrap; font-family: var(--font-mono); font-size: .78rem; color: var(--ink-2); background: var(--wash); padding: 8px 10px; border-radius: 4px; }
.verdict { font-size: .82rem; color: var(--ink-2); border-left: 3px solid var(--series-2); padding-left: 8px; }

@media (prefers-reduced-motion: no-preference) { nav.tabs a, .quick button { transition: background-color .15s, color .15s; } }
@media print { header.top { position: static; } }

/* the React shell */
#root { min-height: 100%; }
.doc.body { font-size: .92rem; max-width: none; }
.doc.body p { margin: 0 0 .6em; }